NOVEL MUTATIONS EVADING AVIAN IMMUNITY AROUND THE RECEPTOR BINDING SITE OF THE CLADE 2.3.2.1C HEMAGGLUTININ GENE REDUCE VIRAL THERMOSTABILITY AND MAMMALIAN PATHOGENICITY

Since 2007, highly pathogenic clade 2.3.2 H5N1 avian influenza A (A(H5N1)) viruses have evolved to clade 2.3.2.1a, b, and c; currently only 2.3.2.1c A(H5N1) viruses circulate in wild birds and poultry.During antigenic evolution, clade 2.3.2.1a and c A(H5N1) viruses acquired both S144N and V223I mutations around the receptor binding site of hemagglu

Hoteliers clearly believe that location is important for a hotel, and have market research evidence to support this.However, almost nothing has been done to enable this issue to be incorporated into revenue generation.There is a gap in the literature relating to analysis from a location-side approach for increase revenue.This study therefore is unt

Ewing sarcoma (ES) is a rare malignancy of the young, primarily arising from the bones.Uncommonly, it can arise extraskeletally and, among the rarest cases, from the spinal extradural tissues.The patient is a previously well 26-year-old male who presented with radicular low back pain.Magnetic resonance imaging revealed an L5-S1 Headers/IDC spinal c

In the current auction-based electricity market, Headers/IDC the design of utility-scale renewable energy systems has traditionally been driven by the levelised cost of energy (LCoE).However, the market is gradually moving towards a subsidy-free era, which will expose the power plant owners to the fluctuating prices of electricity.This paper presen

Due to the uncertainty of the environment, the captured image may not only degrade but also have uneven brightness distribution.The quality of these images can not meet the input requirements of Headers/IDC existing computer vision tasks, so they may lead to performance degradation in the completion of computer vision tasks.Past methods are often o